Chemical synthesis and post-synthesis modification: Water soluble MQDs were synthesized using a method established in our laboratory at SUNUM (Patent Appl. No. PCT/TR2020/050115 and SU IP disclosure No. SUO175, date: 22/10/2019) in a three-step chemical reaction involving pure QDs made of core CdSe coated with gradient layers of CdS followed by a ZnS capping layer. Post-synthesis modification of synthesized CdSe/CdS/ZnS nanocrystals were subjected to ligand exchange reaction and chemical activation and the nanocrystals were made water soluble with available free -COOH and -NH2 functionalities for customers to use for their desired application.
Available quantities: 5 mg, 10 mg and 20 mg vials in one week time duration 50 mg and above 15~30 days
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Magnetic Quantum Dots Orange (MQDs-Bright Orange) in water
MQDs-orange are specifically designed and developed to meet the requirements of Point-of-Care bioassays, imaging, drug-delivery, display and sensor technological industry for downconverting materials. The nanomaterial has unique multimodal functionality with magnetic, photoluminescence and chemical along with high reliability. The material has free -COOH and -NH2 functionality readily available for customized conjugation/linking with desired molecules, drugs, proteins or antibodies. The material has high watersolubility and compatible with physiological saline or PBS.
Early diagnosis of a progressive cancer disease is currently limited due to lack of adequate point-of-care (PoC) diagnostic tools. PoC diagnosis enables detecting early signs of a disease and ave way to disease prevention.Here, we developed an immuno-optomagnetic quantum dots based PoC assay for early detection of a cancer biomarker, human epidermal growth factor receptor-2 (hErbB2) protein in serum. This assay utilizes immunooptomagnetic quantum dots (MQDs-Ab2) nanoarchitectures with unique orientation comprised of core CdSe/ CdS/ZnS QD nanocrystals surrounded by layers of magnetic Fe3O4 nanoparticles (MNPs) and a bioactivated borofloat PoC-chip (Ab1). The MQDs-Ab2 and the PoC-chips were designed to bind same hErbB2 analyte,.. Read More